Woman touching side of her face where profhilo structura is placed to remodel facial fat

Profhilo Structura IN OXFORd

Regenerative Medicine For Natural Facial Lifting


Facial ageing stems from changes in bone, ligaments, muscle, fat and skin. Profhilo Structura targets the superficial fat pads, restoring volume to soften hollows, laxity and the “square” mid-face look. It’s a gentler alternative to dermal fillers, though larger volume loss may still call for fillers alongside Structura.

The treatment infuses a highly diffusive hyaluronic-acid gel that activates stem cells within the fat pads, regenerating fat rather than merely filling space. Minimally invasive and low-discomfort, it subtly lifts the jawline and jowls, with most patients noticing results in 4–8 weeks.

Why choose Profhilo Structura?
✓ Rebuilds the subtle “padding” beneath your skin, gently lifting cheeks, temples and jawline for a naturally refreshed profile
✓ Uses only a handful of tiny injections, so the appointment is quick and bruising is rare
✓ Acts like a deep-conditioning treatment: bathes tissue in long-lasting hydration and sparks fresh collagen, so skin feels both plumper and firmer
✓ Perfect for early sagging or hollow areas that make the face look tired
✓ Results blossom in stages: a soft fullness after two weeks, then smoother, springier skin over the next few months
✓ Works beautifully alongside regular Profhilo, wrinkle relaxers and dermal fillers
✓ Just two sessions a month apart, with a simple 4-6 monthly top-up, keep contours youthful and skin radiantly healthy


What results can you expect With Profhilo Structura ?

Once injected, Profhilo Structura activates ageing adipose fat cell receptors, subtly and safely encouraging them to mimic the behaviour of their youth, supporting the laxity of the skin and soft tissues. After the first treatment, 95% of patients noticed lasting enhancements in the mid-face area.

Studies have shown that Profhilo STRUCTURA can also positively affect skin, ligaments, muscles and even bone integrity. 

The effects of Profhilo STRUCTURA will generally last six months; however, no guarantee can be given for its duration as the product can be affected by internal and external influences, including some medical conditions, medications, smoking and sun exposure.

Combination Treatments

Profhilo Structura is compatible with, and often compliments, many of our other aesthetic treatments, such as Profhilo (for superficial skin tightening and remodelling)dermal filler (for deep volume or structure), and HIFU skin tightening. You should always check with your practitioner that it is suitable if you are having treatments elsewhere.


Ready To Book?

Your journey starts with a personalised consultation and bespoke treatment plan tailored to you. This ensures you receive the most suitable treatment for successful results.


Profhilo Structura | Frequently Asked Questions

  • Profhilo Structura is a patented NAHYCO® technology from IBSA Pharmaceuticals and is created with thermally stabilised high and low molecular-weight hyaluronic acids. Structura is the only treatment products currently licenced to be injected into the superficial adipose (fat) pads for the biomodulation of lax soft tissues of the face. 

  • No. Dermal fillers are gels of hyaluronic acid that have been stabilised with a chemical to keep it held together and replace biological shape or volume in specific areas of the face. It does not have any regenerative or stumilating benefits.

    Structura is a unique hybrid hyaluronic acid gel that has been thermally stabilised (no chemical addition) and is not held together. This allows the product to spread uniformly within the fat pad compartment, where its unique formula stimulates stem cell activity to communicate with fat cells.

  • You will initially require 2-3 treatments spaced 4 weeks apart. Profhilo Structura requires continuous maintenece with a single top up treatment every 4-6 months. This will be discussed with your practitioner as it depends upon your degree of ageing, fat loss, and lifestyle.

  • Yes, every medical treatment carries some risks and these will be fully explained during consultation. However you may find it comforting to know that there have never been any significant adverse events recorded for Profhilo Structura and the main side effects being that of potential bruises from the injection site and mild swelling for 1-2 days. You may notice the product sitting under the skin during this time. Many patients comment that it is barely noticable, wherease some state it is defined for a few days.

  • You may develop a bruise from each injection site (one on each rear side of the face) and you may experience some swelling for 1-2 days after. You may notice the product sitting under the skin during this time. Many patients comment that it is barely noticable, wherease some state it is defined for a few days.

  • You will most likely see results 4 weeks after the initial treatment. 95% of patients do. However it is important to complete the initial course of 2 treatments, four weeks apart, in order to fully see the benefits. You will see the final effects show around 8 weeks after starting your course.

  • Yes, and this will be fully discussed and written for you following your treatment. However it may be helpful to know the following:

    • Do not massage the treatment area. The product will naturally diffuse to where it needs to go over 48 hours.

    • Avoid physical strain and sports for 24 hours.

    • Avoid having further cosmetic procedures for 48 hours.

    • It is not recommended to have sauna or steamy bath for the first few days either.

    • It’s best to stay out of the sun if any bruising or prolonged swelling occurs.

  • The effects of Profhilo Structura will usually last around 6 months. As Structura gradually breaks down in the fat layer, your stem cells will no longer be activated and will return to a more sluggish ability, and the fat cells will begin to shrink again.

    We advise booking your first single maintenance treatment 6 months from starting your initial course of 2, and then a single treatment every 4-6 months.


Still Have Questions?

That’s understandable, and we’ll do our very best to ensure you are fully informed.

Our patient support team are just a call or email away.